Omega-3: the architect of your cellular health
Fats are not the problem – the wrong fats are. Each of your 70 trillion body cells is surrounded by a layer of fat. If omega-3 is missing there, the cell walls become rigid and inflammation cannot heal.
The result: Premature skin aging, cognitive decline and an increased cardiovascular risk. Calculate your individual requirement.
1 · Therapeutic focus
2 · Lab value known?
3 · Your data
Needed to fill the deficit within 3 months. A follow-up measurement is recommended afterwards.
Your personal dose to permanently maintain the index you have reached.
A guidance value based on your weight and general recommendations. Since over 90 % of the population is undersupplied, this is a sensible starting point. For a targeted treatment plan we recommend an index measurement.
Have your index measured precisely – in Herzogenaurach
We do not rely on estimates. In our practice we determine your exact HS-Omega-3 Index through a leading specialist laboratory. Only on this data basis do we create your personal treatment plan.
Book an omega-3 diagnostic appointment → Dr. med. Thomas Ackermann · Specialist in Anesthesiology · HerzogenaurachOmega-3: more than a heart-protection agent
EPA and DHA are essential – your body cannot produce them itself. The supply situation in Germany is inadequate for 90 % of the population.
Every cell membrane in your body consists partly of omega-3 fatty acids. If they are missing, membranes become more rigid, inflammatory signals are broken down less effectively, and cell function suffers:
- 01.Heart & vessels: Meta-analyses show a reduction in cardiovascular events at an index above 8 %. REDUCE-IT study (Bhatt et al., NEJM 2019): high-dose EPA reduced cardiovascular events by 25 %.
- 02.Skin appearance: DHA stabilizes the epidermal lipid barrier. EPA inhibits arachidonic-acid-mediated inflammatory cascades – measurable in acne, rosacea and premature aging.
- 03.Brain & mood: The brain consists of 60 % lipids, with DHA making up the largest share. Associations between a low index and depression as well as cognitive decline are documented.
- 04.Sport & recovery: Omega-3 modulates the resolution of inflammatory responses after exertion. Meta-analyses show a reduction in muscle soreness and an improvement in muscle protein synthesis.
At the practice of Dr. Ackermann we regard the HS-Omega-3 Index as a valid biomarker – not as a wellness metric.
The HS-Omega-3 Index explained
The index measures EPA+DHA as the percentage share of fatty acids in the erythrocyte membrane – a 3-month average, not a daily snapshot.
Omega-6/omega-3 ratio: No less important than the absolute level. The Western diet typically provides a ratio of 15:1 to 20:1. Optimal would be 4:1 or better. A high omega-6 share competes with omega-3 for the same enzyme pathways and reduces the effective benefit.
The specialist diagnostics
We do not rely on estimates. In our practice we determine your exact HS-Omega-3 Index® and the omega-6/omega-3 ratio through a leading specialist laboratory.
Only on this valid data basis do we create your individual treatment plan – with a specific boost and maintenance dose.
Costs: A precise fatty-acid analysis at the specialist laboratory costs approximately on request (self-pay, GOÄ).
Oil vs. capsules – which is better?
To achieve a therapeutic effect (index above 8 %), you need approximately 2,000–3,000 mg EPA/DHA daily.
With standard drugstore capsules (300–500 mg EPA/DHA) you would need 5–10 capsules a day. High-quality oil delivers the same amount in one tablespoon.
Important: The nature-identical triglyceride form (TG) has up to 70 % better bioavailability than synthetic ethyl-ester concentrates (EE). Pay attention to the formulation. (Dyerberg et al., 2010)
What to look for when choosing
The omega-3 market is confusing. Most products on the drugstore shelf are underdosed for a therapeutic effect.
Quality criteria for EPA/DHA preparations
Maintenance dose: Calculated as ~25 mg EPA/DHA per kg body weight per day – consistent with clinical guidelines (1,500–2,000 mg/day for 70 kg).
Boost dose: Each additional 1 g EPA/DHA per day raises the HS-Omega-3 Index by about 1–2 % over 3 months. We use ~400 mg extra per 1 % of deficit. Formula: boost = maintenance + (deficit × 400 mg). (Stark et al., J Nutr 2016)
Limitations: Individual absorption, omega-6 consumption, genetics (FADS1/FADS2 polymorphisms) and dietary habits influence the actual response. A follow-up index after 3 months is indispensable.
- Bleeding time: High doses (above 3 g/day) slightly prolong the bleeding time. With anticoagulants (Marcumar, ASA, NOACs), medical consultation is mandatory.
- EFSA UL: 5 g/day EPA+DHA is classified as safe (EFSA 2012). Above this limit, medical supervision is recommended.
- Rancid oil: Oxidized lipids can be pro-inflammatory. Pay attention to the TOTOX value and correct storage.
- Atrial fibrillation: At very high doses (4 g/day as in REDUCE-IT) a slightly increased risk. For standard doses (below 2 g/day) no increased risk has been demonstrated.
Naming product recommendations by physicians on their practice website are prohibited under §27 (3) MBO-Ä of the professional code of conduct. The Cologne Regional Court confirmed in a ruling of 14 Nov 2024 (case no. 88 O 45/24) that even indirect advertising for supplement manufacturers on physicians' websites is not permitted.
Instead of brand recommendations, we give you the quality criteria by which you can recognize a high-quality product yourself: TG form, TOTOX value, EPA/DHA concentration and independent lab certification.
The diagnostics: A fatty-acid analysis at the specialist laboratory costs, as a self-pay service, approximately on request.
The therapy: High-quality omega-3 oil (TG form) costs, at a therapeutic dosage, approximately on request depending on the product.
DHA is a structural building block of skin lipids and influences the integrity of the epidermal barrier. EPA inhibits the lipoxygenase-mediated inflammatory cascade, which plays a central role in acne, rosacea and dry skin.
Clinical studies show: EPA+DHA reduce UV-induced skin redness and can improve skin hydration. A meta-analysis (Pilkington et al., 2020) found significant improvements in inflammatory acne.
For aesthetic results an index above 8 % is more useful than a single dose – the membrane saturation built up over weeks is what matters.
All information mentioned on this page serves general orientation. This calculator is not a medical device under EU MDR 2017/745. Health data is processed exclusively on the client side. For high doses or existing illnesses, medical consultation is required. · Practice of Dr. med. Thomas Ackermann · Niederndorfer Hauptstraße 41 · 91074 Herzogenaurach · thomas-ackermann.com
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